Mucoproteins of Human Plasma. III. Electrophoretic Studies of Mucoproteins from Perchloric Acid Filtrates of Plasma.

Abstract

The electrophoretic behavior of mucoproteins isolated from perchloric acid filtrates of human plasma has been studied over the pH range of 2 to 8.4. There are at least 3 electrophoretic components in such preparations, the isoelectric points being approximately 2.3, 3.4 and 4.3. The major component has the lowest isoelectric point and travels with a mobility characteristic of α₁-globulin at pH 8.4. The increase in the mucoprotein level isolated from the plasma of a patient with gastric cancer was largely in this acid mucoprotein fraction.