Titration of nicotine intake with full‐length and half‐length cigarettes
- 1 November 1976
- journal article
- research article
- Published by Wiley in Cancer Cell
- Vol. 20 (5), 552-556
- https://doi.org/10.1002/cpt1976205552
Abstract
Titration, the self-regulation of nicotine intake, was studied in 12 smokers by gas chromatograph assays of urinary nicotine levels. Results demonstrated that excretion of urinary nicotine in the proximal condition (half cigarette closer to the filter) did not differ significantly from the whole cigarette condition; however, less nicotine was excreted in the distal condition (half cigarette farther from the filter) because of a rod filtration effect. Subjects extracted proportionately more nicotine from the half than from the whole cigarettes; titration was approximately the same in both half-cigarette conditions. On scales of strength and satisfaction, full-length cigarettes were given the highest rating, followed by proximal and then distal cigarettes.This publication has 1 reference indexed in Scilit:
- The role of nicotine as a determinant of cigarette smoking frequency in man with observations of certain cardiovascular effects associated with the tobacco alkaloidClinical Pharmacology & Therapeutics, 1967