Complexes formed by (pyrimidine)n·(purine)nDNAs on lowering the pH are three-stranded
Open Access
- 1 January 1979
- journal article
- Published by Oxford University Press (OUP) in Nucleic Acids Research
- Vol. 6 (9), 3073-3091
- https://doi.org/10.1093/nar/6.9.3073
Abstract
(Pyrimidine)n·(purine)n DNAs of repeating sequences form a distinctive complex on lowering the pH below 6. Previously this complex was thought to be tetra-stranded. The present work is inconsistent with this view, and four lines of evidence show that the complex consists of a triplex together with a poly d(purine) possessing secondary structure.Keywords
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