FURTHER OBSERVATIONS ON GLOMERULAR FUNCTION

Abstract

In 89 experiments on Necturus extending over 21/2 yrs. the percentage of cases in which the molecular concentration of the glomerular fluid was the same as that of the serum, as compared by Barger''s method, was distinctly correlated with the degree of adequacy of the precautions taken to prevent evaporation of fluid, approaching 100% as the technique approached the ideal. Evidence is offered that the earlier findings of Schmitt and White on inorganic P content of glomerular fluid were due to a dilution of fluid from an external source. Glomerular function is very probably a passive filtration process.