The isolation of 3β-hydroxy-Δ5-steroids from the urine of normal men
- 1 August 1958
- journal article
- research article
- Published by Portland Press Ltd. in Biochemical Journal
- Vol. 69 (4), 596-600
- https://doi.org/10.1042/bj0690596
Abstract
Androst-5-ene-3 [beta], 17 [beta],-diol, androst-5-ene-3 [beta], 17 [beta], [beta]-triol and pregn-5-ene-3 [beta], 17 [alpha], 20[alpha]-triol were isolated from normal male urine which was boiled for 2 hours at neutral pH. By analogy with dehydroepiandrosterone and 16a-hydroxydehydroepiandrosterone it is likely that these steroids are present in urine as the 3 [beta]-sulfates. The metabolism of dehydroepiandrosterone is compared with that of estrone.Keywords
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