LIII.—LEUKOPLAKIA AND CANCER OF THE VULVA

Abstract

Nine years ago, I presented in the Archives a review of my experiences with leukoplakic and malignant lesions of the vulval skin. Since that time I have had considerable additional experience and an opportunity to check up on the final outcome—the five year results—in these cases, so that it seems well to present a brief outline of the conclusions of these investigations. Forty cases of leukoplakia and 76 cases of cancer of the vulva seen since 1906 are the basis of this study. The material has been available in part through the cooperation of my fellow gynecologists and through the reference of cases by Drs. M. F. Engman, W. H. Mook and Richard S. Weiss. In a large majority of these 116 cases, material was obtained for histologic study through a partial or complete vulvectomy or through biopsy excisions. LEUKOPLAKIC VULVITIS First, in regard to the so-called "precancerous" lesions known