MODEL-BASED QUANTIFICATION OF MYOCARDIAL PERFUSION IMAGES FROM SPECT
- 1 December 1989
- journal article
- research article
- Vol. 30 (12), 1992-2001
Abstract
A system for quantitative analysis of myocardial perfusion tomograms is proposed. The system starts with an automated delineation of the total left ventricle, including possible perfusion defects, to determine the mass and shape of the myocardium. Next, polar maps or bulls-eyes are computed from the delineation, which can then be compared to reference bulls-eyes to detect perfusion defects. The proposed system differs in three main aspects from currently available bulls-eye algorithms. First, radial slices are used rather than short-axis slices. In this way three-dimensional gradient information is retianed, in particular near the base and the apex of the left ventricule. Moreover, the reproducibility of this method is expected to be superior, since the interactive selection of short axis slices through the left ventricle is eliminated. Second, the left ventricle is automatically delineated using a flexible computer model in order to obtain higher reproducibility. The resulting delineation contains both mass and shape information. Third, in addition to the classic count rate bulls-eye, a mass bulls-eye is computed, which contains the myocardial mass corresponding to each bulls-eye pixel. Analysis of the count rate bulls-eye reveals perfusion defects, the quantification of the defects is carried out with the mass bulls-eye.This publication has 13 references indexed in Scilit:
- NONISOTROPIC ATTENUATION IN SPECT - PHANTOM TESTS OF QUANTITATIVE EFFECTS AND COMPENSATION TECHNIQUES1987
- USE OF CROSS-CORRELATION FUNCTION TO DETECT PATIENT MOTION DURING SPECT IMAGING1987
- POSITRON IMAGING OF MYOCARDIAL-INFARCTION WITH RB-821986
- AUTOMATED BODY CONTOUR-DETECTION IN SPECT - EFFECTS ON QUANTITATIVE STUDIES1986
- COMPUTER MODELING OF PLANAR MYOCARDIAL PERFUSION IMAGING - EFFECT OF HEART-RATE AND EJECTION FRACTION ON WALL THICKNESS AND CHAMBER SIZE1986
- QUANTIFICATION OF ROTATIONAL TL-201 MYOCARDIAL TOMOGRAPHY1985
- Quantitation of size of relative myocardial perfusion defect by single-photon emission computed tomography.Cell Metabolism, 1984
- QUANTITATIVE-ANALYSIS OF LEFT-VENTRICULAR FUNCTION USING GATED SINGLE PHOTON-EMISSION TOMOGRAPHY1984
- THE SOURCES OF OVERESTIMATION IN THE QUANTIFICATION BY SPECT OF UPTAKES IN A MYOCARDIAL PHANTOM - CONCISE COMMUNICATION1984
- CLINICAL VALIDATION OF FULLY AUTOMATED COMPUTATION OF EJECTION FRACTION FROM GATED EQUILIBRIUM BLOOD-POOL SCINTIGRAMS1983