Catalytic Enantioselective Michael Addition of 1,3-Dicarbonyl Compounds to Nitroalkenes Catalyzed by Well-Defined Chiral Ru Amido Complexes
- 20 August 2004
- journal article
- research article
- Published by American Chemical Society (ACS) in Journal of the American Chemical Society
- Vol. 126 (36), 11148-11149
- https://doi.org/10.1021/ja046296g
Abstract
Well-defined chiral Ru amido complexes promoted asymmetric Michael addition of 1,3-dicarbonyl compounds including malonates, β-keto esters, and 1,3-diketones to nitroalkenes to give the corresponding adducts with excellent ees and in excellent yields.Keywords
This publication has 13 references indexed in Scilit:
- Enantioselective Michael Reaction Catalyzed by Well-Defined Chiral Ru Amido Complexes: Isolation and Characterization of the Catalyst Intermediate, Ru Malonato Complex Having a Metal−Carbon BondJournal of the American Chemical Society, 2003
- Enantioselective Michael Addition of Nitromethane to α,β-Enones Catalyzed by Chiral Quaternary Ammonium Salts. A Simple Synthesis of (R)-BaclofenOrganic Letters, 2000
- Rhodium-Catalyzed Asymmetric Conjugate Addition of Organoboronic Acids to NitroalkenesJournal of the American Chemical Society, 2000
- Catalytic Enantioselective Conjugate Addition of 1,3-Dicarbonyl Compounds to NitroalkenesJournal of the American Chemical Society, 1999
- The Catalyst Precursor, Catalyst, and Intermediate in the RuII‐Promoted Asymmetric Hydrogen Transfer between Alcohols and KetonesAngewandte Chemie-International Edition, 1997
- Asymmetric Transfer Hydrogenation Catalyzed by Chiral Ruthenium ComplexesAccounts of Chemical Research, 1997
- Asymmetric Transfer Hydrogenation of Aromatic Ketones Catalyzed by Chiral Ruthenium(II) ComplexesJournal of the American Chemical Society, 1995
- Asymmetric synthesis of the Novel Antidepressant RolipramAdvanced Synthesis & Catalysis, 1994
- Enantioselective Synthesis of the Antidepressant Rolipram by Michael Addition to a NitroolefinAngewandte Chemie-International Edition, 1992
- Tungsten and molybdenum 2-oxaallyl [.eta.1-(C)-enolate] complexes: functional group transformations, photochemical aldol reactions, and alkyne/carbon monoxide migratory insertion reactionsJournal of the American Chemical Society, 1987