The Biology of Head and Neck Cancer: Detection and Control by Parallel Histologic Sections
- 1 March 1984
- journal article
- research article
- Published by American Medical Association (AMA) in JAMA Otolaryngology–Head & Neck Surgery
- Vol. 110 (3), 193-196
- https://doi.org/10.1001/archotol.1984.00800290057012
Abstract
• Microscopic fingers of epidermoid cancer can extend submucosally 1 to 3 cm from grossly discernible borders of upper aerodigestive tract cancers. These fingers are best detected by sectioning all surgical margins parallel to the margins. Microscopic disease was found at the original excisional margins in 75% of 70 cases. Using this principle for frozen-section evaluation, and reexcising further tissue as indicated, local disease was completely controlled in all 24 patients eligible for two-year follow-up. (Arch Otolaryngol 1984;110:193-196)This publication has 8 references indexed in Scilit:
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