Metalloprotease cleavage of the N terminus of the orphan G protein–coupled receptor GPR37L1 reduces its constitutive activity

Abstract
The N terminus of the receptor GPR37L1 enables constitutive signaling to Gα s .
Funding Information
  • National Health and Medical Research Council of Australia (NHMRC) (573732, 1074386)
  • NHMRC
  • National Heart Foundation of Australia C.J. Martin Fellowship
  • Australian Postgraduate Awards
  • Simon and Michal Wilkenfeld Scholarship