Pseudoprecocious Puberty in Girls as a Result of Estrogen Ingestion

Abstract

THE purpose of this paper is to report 2 cases of precocious secondary sexual development resulting from the ingestion of estrogenic substances by young girls, to point out the clinical peculiarities of this type of sexual precocity and to emphasize the importance of including estrogen ingestion in the differential diagnosis of pseudopuberty in females.Case ReportsCase 1. A 4 - 3/12-year-old girl was referred to the hospital because of tenderness and enlargement of both breasts, together with dark pigmentation of the areolae, of 3 weeks' duration. Two days before admission scanty vaginal bleeding had occurred.The family history was . . .