Epithelial Origin of Polyoma Salivary Tumors in Mice: Evidence Based on Chromosome-Marked Cells
- 29 January 1971
- journal article
- other
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 171 (3969), 394-397
- https://doi.org/10.1126/science.171.3969.394
Abstract
Trypsin dissection of epithelium from mesenchyme of salivary gland rudiments allows reassembly of glands having either epithelium or mesenchyme selectively marked by T6 chromosomes. Virus-induced tumors in such glands invariably bear the karyotype of the epithelial component. The method solves a specific example from a group of classical problems concerning epithelial as opposed to mesenchymal origin of neoplasms.Keywords
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