Transposable Elements in Lactococci: A Review
- 1 January 1993
- journal article
- review article
- Published by American Dairy Science Association in Journal of Dairy Science
- Vol. 76 (1), 1-19
- https://doi.org/10.3168/jds.s0022-0302(93)77318-x
Abstract
Genetic studies have identified the presence of transposable elements within the genus Lactococcus, which includes industrially important microorganisms used in the production of fermented dairy products. Three insertion sequences have been fully characterized in addition to several reports of transpositionlike events. The three insertion sequence elements, ISS1, IS904, and IS981, exhibit the physical and genetic properties characteristic of known insertion sequences. They are closely related to insertion sequences isolated from a wide variety of microorganisms. In lactococci, insertion sequence elements are associated with lactose and sucrose metabolism, proteinase activity, nisin production and immunity, conjugal transfer determinants, and bacteriophage resistance, which are attributes significant for growth in a milk environment. The characteristics, involvement in lactococcal evolution, and recent developments as tools for genetic engineering of the lactococcal elements are discussed.Keywords
This publication has 59 references indexed in Scilit:
- Abortive phage infection and restriction/modification activities directed by pTR2030 determinants are enhanced by recombination with conjugal elements in lactococciJournal of General Microbiology, 1990
- Analysis of the Genetic Determinant for Production of the Peptide Antibiotic NisinJournal of General Microbiology, 1990
- Genetics of proteinases of lactic acid bacteriaBiochimie, 1988
- Gene cloning and expression in lactic streptococciFEMS Microbiology Letters, 1987
- IS431, a staphylococcal insertion sequence-like element related to IS26 from Proteus vulgarisGene, 1987
- Conjugative transfer of the transposon Tn919to lactic acid bacteriaFEMS Microbiology Letters, 1985
- Transfer of sucrose fermenting ability, nisin resistance and nisin production intoStreptococcus lactis712FEMS Microbiology Letters, 1984
- Transposable elementsCell, 1980
- Possible Plasmid Nature of the Determinant for Production of the Antibiotic Nisin in Some Strains of Streptococcus lactisJournal of General Microbiology, 1975
- The Effect of Proflavin, Ethidium Bromide and an Elevated Temperature on the Appearance of Nisin-negative Clones in Nisin-producing Strains of Streptococcus lactisJournal of General Microbiology, 1974