Asymmetric synthesis of the enkephalinase inhibitor thiorphan
- 1 May 1985
- journal article
- research article
- Published by American Chemical Society (ACS) in The Journal of Organic Chemistry
- Vol. 50 (11), 1830-1835
- https://doi.org/10.1021/jo00211a008
Abstract
No abstract availableKeywords
This publication has 12 references indexed in Scilit:
- Membrane-bound kidney neutral metalloendopeptidase: interaction with synthetic substrates, natural peptides, and inhibitorsBiochemistry, 1983
- Inhibition of enkepha,in metabolism by, and antinociceptive activity of, bestatin, an aminopeptidase inhibitorEuropean Journal of Pharmacology, 1983
- Inhibition of procine kidney “enkephalinase” by substituted-N-carboxymethyl dipeptidesBiochemical and Biophysical Research Communications, 1982
- Potentiation of [D-Ala2]enkephalinamide analgesia in rats by thiorphanEuropean Journal of Pharmacology, 1982
- Nociception, enkephalin content and dipeptidyl carboxypeptidase activity in brain of mice treated with exopeptidase inhibitorsNeuropharmacology, 1982
- Selective Protection of Methionine Enkephalin Released from Brain Slices by Enkephalinase InhibitionScience, 1981
- The enkephalinase inhibitor thiorphan shows antinociceptive activity in miceNature, 1980
- Rational design of enkephalinase inhibitors: Substrate specificity of enkephalinase studied from inhibitory potency of various dipeptidesBiochemical and Biophysical Research Communications, 1980
- Two distinct enkephalinases: Solubilization, partial purification and separation from angiotensin converting enzymeLife Sciences, 1979
- Local Anesthetics with Enhanced Affinity for ProteinsJournal of Medicinal Chemistry, 1967