The human solute carrier family 11 member 1 protein (SLC11A1): linking infections, autoimmunity and cancer?
Open Access
- 1 April 2007
- journal article
- review article
- Published by Oxford University Press (OUP) in FEMS Immunology & Medical Microbiology
- Vol. 49 (3), 324-329
- https://doi.org/10.1111/j.1574-695x.2007.00231.x
Abstract
SLC11A1 is known to link infections, autoimmunity and cancers. A review is presented of the mechanisms by which a balance is maintained between infections caused by pathogens (viral, bacterial and protozoan; intracellular and extracellular) and disorders resulting from (acute or chronic) inflammation, and of the interactions that determine how the initial innate immune system directs subsequent acquired immune responses in human populationsKeywords
This publication has 54 references indexed in Scilit:
- Association between SLC11A1 polymorphisms and susceptibility to different clinical forms of tuberculosis in the Peruvian populationInfection, Genetics and Evolution, 2006
- Adeno‐associated virus (AAV) serotypes 2, 4 and 5 display similar transduction profiles and penetrate solid tumor tissue in models of human gliomaThe Journal of Gene Medicine, 2006
- Papillomavirus virus-like particles as vehicles for the delivery of epitopes or genesArchiv für die gesamte Virusforschung, 2006
- Cooperative Activity of BRG1 and Z-DNA Formation in Chromatin RemodelingMolecular and Cellular Biology, 2006
- Crystal structure of a junction between B-DNA and Z-DNA reveals two extruded basesNature, 2005
- TGF-β1 maintains suppressor function and Foxp3 expression in CD4+CD25+ regulatory T cellsThe Journal of Experimental Medicine, 2005
- SLC11A1 (formerly NRAMP1) and susceptibility to visceral leishmaniasis in The SudanEuropean Journal of Human Genetics, 2003
- Polymorphism ofSLC11A1(FormerlyNRAMP1) Gene Confers Susceptibility to Kawasaki DiseaseThe Journal of Infectious Diseases, 2003
- ATF3 Represses 72-kDa Type IV Collagenase (MMP-2) Expression by Antagonizing p53-dependent trans-Activation of the Collagenase PromoterPublished by Elsevier BV ,2002
- Natural Resistance to Infection with Intracellular Pathogens: The Nramp1 Protein Is Recruited to the Membrane of the PhagosomeThe Journal of Experimental Medicine, 1997