Laparoscopic Colorectomy for Colorectal Cancer: Retrospective Analysis of 889 Patients in a Single Center
Open Access
- 1 January 2012
- journal article
- Published by Tohoku University Medical Press in The Tohoku Journal of Experimental Medicine
- Vol. 227 (3), 171-177
- https://doi.org/10.1620/tjem.227.171
Abstract
Laparoscopic colectomy has been reported as an alternative for treatment of colorectal cancer. However, its long-term efficacy and safety remain obscure. The purpose here was to review our experience with laparoscopic colectomy in 899 patients between June 2001 and December 2008. Of them, 43 patients were converted to open surgery and 846 accepted laparoscopic colorectomy successfully. Among these 846 patients, 790 patients underwent radical resection and 56 patients underwent palliative resection. Only 1 patient died from perioperative pulmonary infection; thus the mortality was 0.12% (1/846). The morbidity of perioperative complications was 18.20% (154/846): intraoperative complication rate was 4.49% (38/846) and the most common intraoperative complication was subcutaneous emphysema and hypercapnia (1.65%, 14/846); postoperative complication rate was 13.71% (116/846) and the most common postoperative complication was ileus (4.37%, 37/846). The overall followed-up rate was 86.41% (731/846, 680 for radical operations and 51 palliative operations). Postoperative deaths happened to 139 patients, including 112 after radical operation and 27 after palliative resection. Of these 112 patients, 97 deaths were cancer-related (14.26%, 97/680) and 15 deaths were non-cancer-related. There were 10 patients encountered local recurrence (1.47%, 10/680) and 105 for metastasis (15.44%, 105/680) after radical operation. Forty-two patients are still alive with tumor. Overall survival rate was 80.98% (592/731), 3-year disease-free survival (DFS) rate after radical operation was 78.0%, and 3-year DFS rate after radical operation for stage I, stage II, and stage III was 89.0%, 85.0%, and 65.0%, respectively. In conclusion, laparoscopic colorectal resection is a feasible and safe technology for colorectal cancer.Keywords
This publication has 19 references indexed in Scilit:
- Laparoscopic resection for colorectal cancerBritish Journal of Surgery, 2008
- Laparoscopic Colectomy for Cancer Is Not Inferior to Open Surgery Based on 5-Year Data From the COST Study Group TrialAnnals of Surgery, 2007
- Multidimensional Analysis of Learning Curves in Laparoscopic Sigmoid ResectionDiseases of the Colon & Rectum, 2003
- Laparoscopy-assisted colectomy versus open colectomy for treatment of non-metastatic colon cancer: a randomised trialThe Lancet, 2002
- Hand-assisted laparoscopic colorectal surgerySurgical Endoscopy, 2000
- A Prospective, Randomized Trial Comparing Laparoscopic Versus Conventional Techniques in Colorectal Cancer Surgery: A Preliminary ReportJournal of the American College of Surgeons, 1998
- The Learning Curve for Laparoscopic Colorectal SurgeryArchives of Surgery, 1997
- Laparoscopic-assisted colectomy with the dexterityTM pneumo sleeveDiseases of the Colon & Rectum, 1996
- Early results of laparoscopic surgery for colorectal cancerDiseases of the Colon & Rectum, 1996
- Impact of pneumoperitoneum on trocar site implantation of colon cancer in hamster modelDiseases of the Colon & Rectum, 1995