DNA Helicases Required for Homologous Recombination and Repair of Damaged Replication Forks

1 December 2006

journal article
review article
Published by Annual Reviews in Annual Review of Genetics

Vol. 40 (1), 279-306
https://doi.org/10.1146/annurev.genet.40.110405.090636

Abstract

DNA helicases are found in all kingdoms of life and function in all DNA metabolic processes where the two strands of duplex DNA require to be separated. Here, we review recent developments in our understanding of the roles that helicases play in the intimately linked processes of replication fork repair and homologous recombination, and highlight how the cell has evolved many distinct, and sometimes antagonistic, uses for these enzymes.

Keywords

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