Assignment of a structural gene for?-glucuronidase to human chromosome C7
- 1 September 1976
- journal article
- Published by Springer Science and Business Media LLC in Somatic Cell and Molecular Genetics
- Vol. 2 (5), 401-410
- https://doi.org/10.1007/bf01542721
Abstract
An electrophoretic technique was developed which allows the separation of human β-glucuronidase (GUS EC 3.2.1.31) from the enzyme present in cultured murine, Chinese and Syrian hamster cells in one buffer system on Cellogel. Using this technique a number of independent human-mouse somatic cell hybrids have been analyzed for the segregation of GUS, other enzyme markers, and all human chromosomes. The results indicate that a structural gene for human β-glucuronidase is located on chromosome C7.Keywords
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