Neurodegenerative diseases of Guam: Analysis of TAU
- 1 July 1999
- journal article
- Published by Ovid Technologies (Wolters Kluwer Health) in Neurology
- Vol. 53 (2), 411
- https://doi.org/10.1212/wnl.53.2.411
Abstract
Article abstract Mutations in the tau gene have been described in families affected by frontotemporal dementia with parkinsonism linked to chromosome 17. The authors performed a genetic and biochemical analysis of this gene and its product in the parkinsonism dementia complex of Guam, a disorder characterized by the extensive formation of neurofibrillary tangles. The tau gene is not a primary cause of the parkinsonism dementia complex of Guam.Keywords
This publication has 7 references indexed in Scilit:
- Phosphorylation of specific sets of tau isoforms reflects different neurofibrillary degeneration processesFEBS Letters, 1998
- Mutation in the tau gene in familial multiple system tauopathy with presenile dementiaProceedings of the National Academy of Sciences, 1998
- Association of missense and 5′-splice-site mutations in tau with the inherited dementia FTDP-17Nature, 1998
- Tau is a candidate gene for chromosome 17 frontotemporal dementiaAnnals of Neurology, 1998
- Neurodegenerative diseases with cytoskeletal pathology: A biochemical classificationAnnals of Neurology, 1997
- Identification of Phosphorylation Sites in PHF-TAU from Patients with Guam Amyotrophic Lateral Sclerosis/Parkinsonism-dementia ComplexJournal of Neuropathology and Experimental Neurology, 1996
- Guamanian neurodegenerative diseaseNeurology, 1995