Haptoglobin Groups and Transferrin Subtypes in Multiple Myeloma
- 1 January 1988
- journal article
- research article
- Published by S. Karger AG in Human Heredity
- Vol. 38 (2), 117-121
- https://doi.org/10.1159/000153769
Abstract
Haptoglobin and transferrin types were determined for 27 multiple myeloma patients and a series of case controls. No association was found between haptoglobin and the disease, which confirms the findings of an earlier investigation. However, we found a significantly increased relative risk of 2.6 for TFCICI individuals. It is suggested that the role of transferrin in erythropoiesis and cell proliferation of both malignant and normal cells, may, at least in part, explain the association. Of additional relevance may be the suggestion that TFClCI individuals have higher blood iron levels than other subtypes.Keywords
This publication has 10 references indexed in Scilit:
- Specific cognitive effects of mild iron deficiency and associations with blood polymorphisms in young adultsAnnals of Human Biology, 1986
- Transferrin in Disease. I: A Potential Prognostic Indicator in Patients Undergoing Bone Marrow TransplantationAmerican Journal of Clinical Pathology, 1984
- GENETIC-ASPECTS OF SUSCEPTIBILITY TO MULTIPLE-MYELOMA1982
- Human cell surface glycoprotein related to cell proliferation is the receptor for transferrin.Proceedings of the National Academy of Sciences, 1981
- A new procedure for the determination of transferrinC (TfC) subtypes by isoelectric focusingHuman Genetics, 1980
- Identification of transferrin receptors on the surface of human cultured cells.Proceedings of the National Academy of Sciences of the United States of America, 1979
- A study on the association between myelomatosis and immunoglobulin allotypes, HLA, and blood groupsImmunogenetics, 1976
- THE ESTIMATION AND SIGNIFICANCE OF THE LOGARITHM OF A RATIO OF FREQUENCIESAnnals of Human Genetics, 1956
- Zone electrophoresis in starch gels: group variations in the serum proteins of normal human adultsBiochemical Journal, 1955
- ON ESTIMATING THE RELATION BETWEEN BLOOD GROUP AND DISEASEAnnals of Human Genetics, 1955