Synthesis of monofluoro- and difluoro- methylenephosphonate analogues of sn-glycerol-3-phosphate as substrates for glycerol-3-phosphate dehydrogenase and the X-ray structure of the fluoromethylenephosphonate moiety
- 1 January 1996
- journal article
- Published by Elsevier BV in Tetrahedron
- Vol. 52 (1), 165-176
- https://doi.org/10.1016/0040-4020(95)00890-k
Abstract
No abstract availableThis publication has 34 references indexed in Scilit:
- N-α-Fmoc-4-phosphono(difluoromethyl)-L-phenylalanine: A new O-phosphotyrosine isosteric building block suitable for direct incorporation into peptidesTetrahedron Letters, 1994
- Phosphonates as mimics of phosphate biomolecules: ab initio calculations on tetrahedral ground states and pentacoordinate intermediates for phosphoryl transferThe Journal of Organic Chemistry, 1993
- Synthesis of a difluoromethylenephosphonate analogue of AZT 5'-triphosphate and its inhibition of HIV-1 reverse transcriptaseBioorganic & Medicinal Chemistry Letters, 1991
- Fluorine in enzyme chemistry part 2 The preparation of difluoromethylenephosphonate analogues of glycolytic phosphates. Approaching an isosteric and isoelectronic phosphate mimicTetrahedron, 1989
- Synthesis of a difluoromethylenephosphonate analogue of glycerol-3-phosphate. A substrate for NADH linked glycerol-3-phosphate dehydrogenaseJournal of the Chemical Society, Chemical Communications, 1988
- Synthesis of α- and γ-fluoroalkylphosphonatesJournal of the Chemical Society, Perkin Transactions 1, 1985
- The synthesis and metal binding characteristics of novel, isopolar phosphonate analogues of nucleotidesJournal of the Chemical Society, Perkin Transactions 1, 1983
- A novel synthesis of α- and γ- fluoroalkylphosphonatesJournal of the Chemical Society, Chemical Communications, 1981
- Phosphonates as analogues of natural phosphatesChemical Reviews, 1977
- Dehydrogenation of a phosphonate substrate analogue by glycerol 3-phosphate dehydrogenaseBiochemical Journal, 1974