Assessment of Pattern and Shape Symmetry of Bilateral Normal Corneas by Scheimpflug Technology
Open Access
- 30 September 2018
- Vol. 10 (10), 453
- https://doi.org/10.3390/sym10100453
Abstract
Purpose: The aim of this study was to assess bilateral symmetry in normal fellow eyes by using optical and geometric morphometric parameters. Methods: All participants underwent complete biocular examinations. Scheimpflug tomography data from 66 eyes of 33 patients were registered. The interocular symmetry was based on five patterns: morphogeometric symmetry, axial symmetry at the corneal vertex, angular-spatial symmetry, direct symmetry (equal octants), and enantiomorphism (mirror octants). Results: No statistically significant differences were found between right and left eyes in corneal morphogeometric (p ≥ 0.488) and aberrometric parameters (p ≥ 0.102). Likewise, no statistically significant differences were found in any of the axial symmetry parameters analyzed (p ≥ 0.229), except in the surface rotation angle beta (p = 0.102) and translation coordinates X0 and Y0 (p < 0.001) for the anterior corneal surface, and the rotation angle gamma (p < 0.001) for the posterior surface. Similarly, no statistically significant differences were identified for direct symmetry (p ≥ 0.20) and enantiomorphism (p ≥ 0.75), except for some elevation data in the posterior surface (p < 0.01). Conclusions: The level of symmetry of both corneas of a healthy individual is high, with only some level of disparity between fellow corneas in rotation and translation references. Abnormalities in this pattern of interocular asymmetry may be useful as a diagnostic tool.Keywords
Funding Information
- Instituto de Salud Carlos III (RD16/0008/0012)
- Ministerio de Economía, Industria y Competitividad, Gobierno de España (RYC-2016-20471)
This publication has 46 references indexed in Scilit:
- Evaluation of the Shape Symmetry of Bilateral Normal Corneas in a Chinese PopulationPLOS ONE, 2013
- A Comprehensive Assessment of the Precision and Agreement of Anterior Corneal Power Measurements Obtained Using 8 Different DevicesPLOS ONE, 2012
- Plasma miR-601 and miR-760 Are Novel Biomarkers for the Early Detection of Colorectal CancerPLOS ONE, 2012
- Intrasubject repeatability of corneal morphology measurements obtained with a new Scheimpflug photography–based systemJournal of Cataract & Refractive Surgery, 2012
- Placido-Based Indices of Corneal IrregularityOptometry and Vision Science, 2011
- Biometry of the Cornea in Myopic Chinese PatientsJournal of Refractive Surgery, 2011
- Evaluation of bilateral minimum thickness of normal corneas based on Fourier-domain optical coherence tomographyJournal of Cataract & Refractive Surgery, 2010
- Axes of astigmatism in fellow eyes show mirror rather than direct symmetryOphthalmic and Physiological Optics, 2008
- Quantitative Analysis of Brain Asymmetry by Using the Divergence Measure: Normal-Pathological Brain DiscriminationAcademic Radiology, 2006
- Biomodels of Bone: A ReviewAnnals of Biomedical Engineering, 2005