Cerebellovascular Disease: Magnetic Resonance Imaging
Open Access
- 19 November 2016
- journal article
- Published by Ubiquity Press, Ltd. in Journal of the Belgian Society of Radiology
- Vol. 100 (1), 94
- https://doi.org/10.5334/jbr-btr.1230
Abstract
The goal of this thesis was to elucidate the details of cerebellovascular diseases with advanced magnetic resonance (MR) imaging (MRI) and to translate the findings to routine clinical MRI. The first aim was to image cerebellar arterial perfusion territories, which was achieved by applying super-selective arterial spin labelling (ASL) MRI with labelling of both vertebral arteries in addition to the carotid arteries. The second aim was to unravel the imaging patterns of cerebellar infarctions with 7T post-mortem MRI in addition to volume (3D) clinical MRI. This research led to the description of “cerebellar cortical infarct cavities”, an incidental imaging finding that proved to be the most frequent manifestation of cerebellar ischemia as well as a marker of atherosclerotic and thromboembolic cerebrovascular disease. Finally, we found that almost all patients with such cavities lack a clinical history of vertebrobasilar transient ischemic attack (TIA) or stroke, disclosing the still very high incidence of clinically occult ischemia in the posterior fossa.Keywords
This publication has 8 references indexed in Scilit:
- Misinterpretation of ischaemic infarct location in relationship to the cerebrovascular territoriesJournal of Neurology, Neurosurgery & Psychiatry, 2016
- Cerebellar cortical infarct cavities and vertebral artery diseaseNeuroradiology, 2016
- Selective Arterial Spin LabelingTopics in Magnetic Resonance Imaging, 2016
- Cerebellar Cortical Infarct CavitiesStroke, 2015
- Cerebellar infarct patterns: The SMART-Medea studyNeuroImage: Clinical, 2015
- Ischaemic Cavities in the Cerebellum: An ex vivo 7-Tesla MRI Study with Pathological CorrelationCerebrovascular Diseases, 2014
- In vivo visualization of the PICA perfusion territory with super-selective pseudo-continuous arterial spin labeling MRINeuroImage, 2013
- Very Small Cerebellar Infarcts: Integration of Recent Insights into a Functional Topographic ClassificationCerebrovascular Diseases, 2013