Maternal and paternal origin of extra chromosome in trisomy 21
- 1 January 1976
- journal article
- research article
- Published by Springer Science and Business Media LLC in Human Genetics
- Vol. 32 (1), 17-21
- https://doi.org/10.1007/bf00569972
Abstract
Fluorescence markers were studied in 40 patients with Down's syndrome and their parents. In 11 cases maternal and in 5 cases paternal non-disjunction could be shown. The disjunctional event occurred in the first meiotic division in 5 maternal and in 2 paternal cases. A second division failure was found in 4 maternal and 2 paternal cases. In 3 cases the failure could either be of first or second meiotic division origin.This publication has 14 references indexed in Scilit:
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