The highly electrophilic character of 4-chloro-7-nitrobenzofurazan and possible consequences for its applications as a protein-labelling reagent
- 1 April 1977
- journal article
- research article
- Published by Portland Press Ltd. in Biochemical Journal
- Vol. 163 (1), 189-192
- https://doi.org/10.1042/bj1630189
Abstract
4-Chloro-7-nitrobenzofurazan possesses at least one highly electrophilic centre (C-6) that is much more reactive towards nucleophiles than position C-4, the irreversible alkylating site of this reagent. Possible consequences of the electrophilic character of 4-chloro-7-nitrobenzofurazan for its application as a protein-labelling reagent are discussed.This publication has 7 references indexed in Scilit:
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