Molecular characterisation of cell line models for triple-negative breast cancers
Open Access
- 1 January 2012
- journal article
- research article
- Published by Springer Science and Business Media LLC in BMC Genomics
- Vol. 13 (1), 619
- https://doi.org/10.1186/1471-2164-13-619
Abstract
Triple-negative breast cancers (BC) represent a heterogeneous subtype of BCs, generally associated with an aggressive clinical course and where targeted therapies are currently limited. Target validation studies for all BC subtypes have largely employed established BC cell lines, which have proven to be effective tools for drug discovery.Keywords
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