Assessment of a DJ-1 ( PARK7 ) polymorphism in Finnish PD
- 14 October 2003
- journal article
- Published by Ovid Technologies (Wolters Kluwer Health) in Neurology
- Vol. 61 (7), 1000-1002
- https://doi.org/10.1212/01.wnl.0000083992.28066.7e
Abstract
Mutations in DJ-1 are a cause of autosomal recessive parkinsonism. Polymorphism of genes implicated in hereditary forms of parkinsonism may be a predisposing factor in sporadic Parkinson’s disease (PD). The authors analyzed whether a polymorphism (g.168_185del) within exon 1 of DJ-1 contributes to the risk of sporadic PD in a Finnish case-control series. This gene does not play a major role in the genetic predisposition to PD in this population.Keywords
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