Understanding electrokinetics at the nanoscale: A perspective
- 1 March 2009
- journal article
- Published by AIP Publishing in Biomicrofluidics
- Vol. 3 (1), 012001
- https://doi.org/10.1063/1.3056045
Abstract
Electrokinetics promises to be the microfluidic technique of choice for portable diagnostic chips and for nanofluidic molecular detectors. However, despite two centuries of research, our understanding of ion transport and electro-osmotic flow in and near nanoporousmembranes, whose pores are natural nanochannels, remains woefully inadequate. This short exposition reviews the various ion-flux and hydrodynamic anomalies and speculates on their potential applications, particularly in the area of molecular sensing. In the process, we revisit several old disciplines, with some unsolved open questions, and we hope to create a new one.Keywords
This publication has 26 references indexed in Scilit:
- Fabrication and functionalization of single asymmetric nanochannels for electrostatic/hydrophobic association of protein moleculesNanotechnology, 2008
- Dynamic superconcentration at critical-point double-layer gates of conducting nanoporous granules due to asymmetric tangential fluxesBiomicrofluidics, 2008
- Focusing-enhanced mixing in microfluidic channelsBiomicrofluidics, 2008
- Dielectrophoretic discrimination of bovine red blood cell starvation age by buffer selection and membrane cross-linkingBiomicrofluidics, 2007
- Nanobead electrokinetics: The enabling microfluidic platform for rapid multi‐target pathogen detectionAIChE Journal, 2007
- Electrohydrodynamics around single ion-permselective glass beads fixed in a microfluidic deviceMicrofluidics and Nanofluidics, 2007
- An integrated dielectrophoretic chip for continuous bioparticle filtering, focusing, sorting, trapping, and detectingBiomicrofluidics, 2007
- Open-tubular capillary electrochromatography-mass spectrometry with sheathless nanoflow electrospray ionization for analysis of amino acids and peptidesJournal of Mass Spectrometry, 2006
- Capture and release of viruses using amino-functionalized silica particlesAnalytica Chimica Acta, 2006
- Front interaction on a ring electrodePhysical Review E, 1998