THE RELATION OF BLOOD VOLUME REDUCTION TO MORTALITY RATE IN HEMORRHAGIC AND TRAUMATIC SHOCK IN DOGS

Abstract

The authors'' quantitative data show that in the hemorrhage series the residual blood vol. at 50% mortality (L.H.5O) is 59.1 [plus or minus] 2.9 ml./kg. of body wt., whereas in the trauma series the L.H.5O is 73.4 [plus or minus] 3.0 ml./kg. of body wt. The difference between the L.H.5O values for these 2 groups is statistically significant. This indicates that the loss of the circulating blood vol. alone is not adequate to explain the high mortality rate in traumatized dogs. The traumatized animals as compared with hemorrhaged animals have early tachycardia exceeding 200 beats/min., high mean blood pressure, high hematocrit values, early depression of the central nervous system, and according to other investigators high calculated peripheral resistance and high fluorescein circulation time.