PREPARATION AND PROPERTIES OF TRITIATED HUMANβ‐ENDORPHIN WITH HIGH SPECIFIC RADIOACTIVITY
- 1 November 1978
- journal article
- research article
- Published by Wiley in International Journal of Peptide and Protein Research
- Vol. 12 (5), 325-326
- https://doi.org/10.1111/j.1399-3011.1978.tb02904.x
Abstract
Tritiated human .beta.-endorphin, specifically labeled at Tyr27, was prepared with 50 Ci/mmol. Various physicochemical investigations indicated that triatiated peptide is identical with the native Bh-endorphin. Opiate activity of the tritiated product possesses the same potency as the native peptide.Keywords
This publication has 4 references indexed in Scilit:
- β-endorphin: A pituitary peptide with potent morphine-like activityArchives of Biochemistry and Biophysics, 1977
- The synthesis and opiate activity of β-endorphinBiochemical and Biophysical Research Communications, 1976
- The effects of adrenaline, noradrenaline and isoprenaline on inhibitory α‐ and β‐adrenoceptors in the longitudinal muscle of the guinea‐pig ileumBritish Journal of Pharmacology, 1970
- Solid Phase Peptide Synthesis. I. The Synthesis of a TetrapeptideJournal of the American Chemical Society, 1963