Optoelectronic method for detection of cervical intraepithelial neoplasia and cervical cancer
Open Access
- 1 January 2011
- journal article
- Published by Polish Academy of Sciences Chancellery in Opto-Electronics Review
- Vol. 19 (4), 478-485
- https://doi.org/10.2478/s11772-011-0040-4
Abstract
The optoelectronic method is one of the most promising concepts of biophysical program of the diagnostics of CIN and cervical cancer. Objectives of the work are evaluation of sensitivity and specificity of the optoelectronic method in the detection of CIN and cervical cancer. The paper shows correlation between the pNOR number and sensitivity/specificity of the optoelectronic method. The study included 293 patients with abnormal cervical cytology result and the following examinations: examination with the use of the optoelectronic method — Truscreen, colposcopic examination, and histopathologic biopsy.Specificity of the optoelectronic method for LGSIL was estimated at 65.70%, for HGSIL and squamous cell carcinoma of cervix amounted to 90.38%. Specificity of the optoelectronic method used to confirm lack of cervical pathology was estimated at 78.89%.The field under the ROC curve for the optoelectronic method was estimated at 0.88 (95% CI, 0.84–0.92) which shows high diagnostic value of the test in the detection of HGSIL and squamous cell carcinoma.The optoelectronic method is characterised by high usefulness in the detection of CIN, present in the squamous epithelium and squamous cell carcinoma of cervix.Keywords
This publication has 7 references indexed in Scilit:
- The global health burden of infection‐associated cancers in the year 2002International Journal of Cancer, 2006
- A real time optoelectronic device as an adjunct to the Pap smear for cervical screening: A multicenter evaluationInternational Journal of Gynecologic Cancer, 2003
- A real time optoelectronic device as an adjunct to the Pap smear for cervical screening: A multicenter evaluationInternational Journal of Gynecologic Cancer, 2003
- Modelling of epithelial tissue impedance measured using three different designs of probePhysiological Measurement, 2003
- Human papillomavirus is a necessary cause of invasive cervical cancer worldwideThe Journal of Pathology, 1999
- An electronic approach to the detection of pre-cancer and cancer of the uterine cervix: a preliminary evaluation of PolarprobeInternational Journal of Gynecologic Cancer, 1994
- NATURAL HISTORY OF CERVICAL INTRAEPITHELIAL NEOPLASIAClinical Obstetrics and Gynecology, 1967