Characteristics of the oral lesions in patients with cutaneous recurrent erythema multiforme
- 1 January 1995
- journal article
- Published by Wiley in Journal of Oral Pathology & Medicine
- Vol. 24 (1), 9-13
- https://doi.org/10.1111/j.1600-0714.1995.tb01122.x
Abstract
Erythema multiforme may be recurrent and the oral cavity is often affected. A series of 82 patients with unequivocal recurrent cutaneous erythema multiforme were examined to determine the incidence and nature of oral lesions. Seventy per cent of patients had oral lesions, comprising multiple, large, shallow, extremely painful and debilitating ulcers, which affected the entire oral mucosa in over 20%. The buccal mucosa and tongue were the most frequently affected sites in the remainder and the lips were affected in 13% of patients. Lesions generally lasted for 1-3 weeks. In over 60% of cases these attacks followed an episode of herpes simplex virus infection during the preceding fortnight. Recurrent attacks showed a different site distribution from the initial attacks, with a greater proportion having genital as well as skin and oral mucosal involvement. Detailed case histories of five patients are presented to illustrate the role of azathioprine in treating oral lesions and to document a familial case of recurrent erythema multiforme, with severe mucosal involvement.Keywords
This publication has 28 references indexed in Scilit:
- Detection of Viral DNA Within Skin of Healed Recurrent Herpes Simplex Infection and Erythema Multiforme LesionsJournal of Investigative Dermatology, 1992
- Erythema multiformeCurrent Problems in Dermatology, 1990
- Detection of Herpes Simplex Virus DNA in Cutaneous Lesions of Erythema MultiformeJournal of Investigative Dermatology, 1989
- Recurrent erythema multiforme: a possible role of foodstuffsBritish Dental Journal, 1989
- Multiple recurrence of oral erythema multiforme after secondary herpes simplex: report of case and review of literatureThe Journal of the American Dental Association, 1986
- Recurrent and continuous erythema multiforme- a clinical and immunological studyClinical and Experimental Dermatology, 1985
- Erythema multiforme: Clinical characteristics and natural history in fifty patientsOral Surgery, Oral Medicine, Oral Pathology, 1978
- Erythema multiforme: Review of twenty-six casesOral Surgery, Oral Medicine, Oral Pathology, 1976
- Erythema multiforme affecting the oral cavityOral Surgery, Oral Medicine, Oral Pathology, 1968
- Development of oral lesions in erythema multiforme exudativumOral Surgery, Oral Medicine, Oral Pathology, 1967