Prevalence of inflammatory bowel disease in two districts of Sri Lanka: a hospital based survey
Open Access
- 19 March 2010
- journal article
- research article
- Published by Springer Science and Business Media LLC in BMC Gastroenterology
- Vol. 10 (1), 32
- https://doi.org/10.1186/1471-230X-10-32
Abstract
Background Inflammatory bowel disease (IBD) is being increasingly diagnosed in Asia. However there are few epidemiological data from the region. Methods To determine prevalence and clinical characteristics of IBD, a hospital-based survey was performed in the Colombo and Gampaha districts (combined population 4.5 million) in Sri Lanka. Patients with established ulcerative colitis (UC) and Crohn's disease (CD), who were permanent residents of these adjoining districts, were recruited from hospital registries and out-patient clinics. Clinical information was obtained from medical records and patient interviews. Results There were 295 cases of IBD (UC = 240, CD = 55), of which 34 (UC = 30, CD = 4) were newly diagnosed during the study year. The prevalence rate for UC was 5.3/100,000 (95% CI 5.0-5.6/100,000), and CD was 1.2/100,000 (95% CI 1.0-1.4/100,000). The incidence rates were 0.69/100,000 (95% CI 0.44-0.94/100,000) for UC and 0.09/100,000 (95% CI 0.002-0.18/100,000) for CD. Female:male ratios were 1.5 for UC and 1.0 for CD. Mean age at diagnosis was (males and females) 36.6 and 38.1y for UC and 33.4 and 36.2y for CD. Among UC patients, 51.1% had proctitis and at presentation 58.4% had mild disease. 80% of CD patients had only large bowel involvement. Few patients had undergone surgery. Conclusions The prevalence of IBD in this population was low compared to Western populations, but similar to some in Asia. There was a female preponderance for UC. UC was mainly mild, distal or left-sided, while CD mainly involved the large bowel.Keywords
This publication has 24 references indexed in Scilit:
- Inflammatory bowel disease: A survey of the epidemiology in AsiaJournal of Digestive Diseases, 2009
- Demography and clinical course of ulcerative colitis in a multiracial Asian population: A nationwide study from MalaysiaJournal of Digestive Diseases, 2009
- High frequency of parasitic and viral stool pathogens in patients with active ulcerative colitis: Report from a tropical countryScandinavian Journal of Gastroenterology, 2009
- Emergence of inflammatory bowel disease ‘beyond the West’: do prosperity and improved hygiene have a role?Transactions of the Royal Society of Tropical Medicine and Hygiene, 2008
- Prevalence and Importance of Amebic Infestation in Patients with Ulcerative Colitis in Two Regions in TurkeyDigestive Diseases and Sciences, 2008
- The Montreal classification of inflammatory bowel disease: controversies, consensus, and implicationsGut, 2006
- Rising incidence and prevalence of Crohn’s disease in Asia: Is it apparent or real?Journal of Gastroenterology and Hepatology, 2006
- Retrospective analysis of 515 cases of Crohn’s disease hospitalization in China: Nationwide study from 1990 to 2003Journal of Gastroenterology and Hepatology, 2006
- Incidence of inflammatory bowel disease across Europe: is there a difference between north and south? Results of the European Collaborative Study on Inflammatory Bowel Disease (EC-IBD).Gut, 1996
- Inflammatory bowel disease: An uncommon problem in SingaporeJournal of Gastroenterology and Hepatology, 1992