Rho Kinase Regulates the Survival and Transformation of Cells Bearing Oncogenic Forms of KIT, FLT3, and BCR-ABL
Open Access
- 1 September 2011
- journal article
- research article
- Published by Elsevier BV in Cancer Cell
- Vol. 20 (3), 357-369
- https://doi.org/10.1016/j.ccr.2011.07.016
Abstract
No abstract availableKeywords
Funding Information
- National Institutes of Health (HL085098, R01 CA134777, R01 HL075816, R01 HL077177, R01 HL08111)
- Riley Children's Foundation
This publication has 57 references indexed in Scilit:
- Essential role for focal adhesion kinase in regulating stress hematopoiesisBlood, 2010
- ROCK1 functions as a suppressor of inflammatory cell migration by regulating PTEN phosphorylation and stabilityBlood, 2010
- FLT3-mutant allelic burden and clinical status are predictive of response to FLT3 inhibitors in AMLBlood, 2010
- Requirement for p85α regulatory subunit of class IA PI3K in myeloproliferative disease driven by an activation loop mutant of KITExperimental Hematology, 2008
- Genetic and pharmacologic evidence implicating the p85α, but not p85β, regulatory subunit of PI3K and Rac2 GTPase in regulating oncogenic KIT-induced transformation in acute myeloid leukemia and systemic mastocytosisBlood, 2007
- Patterns of somatic mutation in human cancer genomesNature, 2007
- Efficacy and Safety of Imatinib Mesylate in Advanced Gastrointestinal Stromal TumorsNew England Journal of Medicine, 2002
- Sphingosylphosphorylcholine Is a Novel Messenger for Rho-Kinase–Mediated Ca 2+ Sensitization in the Bovine Cerebral ArteryCirculation Research, 2002
- The effects of the Rho‐kinase inhibitor Y‐27632 on arachidonic acid‐, GTPγS‐, and phorbol ester‐induced Ca2+‐sensitization of smooth muscleFEBS Letters, 1998
- Gain-of-Function Mutations of c- kit in Human Gastrointestinal Stromal TumorsScience, 1998