Chemistry of tissues

Abstract

Polysaccharide-amino-acid complexes with blood group A specificity were prepd. from saliva, hog mucin, pepsin, neopeptone, peptone, beef pancreas, commercial pan-creatin, ovomucoid, frog spawn mucin, damson gum, and human erythrocytes. Alkaline hydrolysis of A substance from pepsin causes degradation and loss of specificity. The stable carbohydrate residue from pepsin A substance was acetylated and methylated and an examination of the hydro-lytic products showed the presence of d-galactose, d-mannose, d-glucosamine, and l-fucose. Part of d-glucosamine and l-fucose are present as terminal groups.