Antigen-presenting cells for Lyt-2+ cells. I. Stimulation of unprimed Lyt-2+ cells by H-2 different Thy-1-Ia- cells prepared from spleen and bone marrow.
- 31 May 1988
- journal article
- research article
- Published by The American Association of Immunologists in The Journal of Immunology
- Vol. 140 (11), 3745-3750
- https://doi.org/10.4049/jimmunol.140.11.3745
Abstract
In agreement with previous studies on Ia- tumor cells, evidence is presented that primary MLR of purified Lyt-2+ T cells to class I alloantigens can be elicited by a minor population of Thy 1- Ia- cells present in normal spleen, bone marrow, and day-13 fetal liver; these cells are non-stimulatory for L3T4+ T cells. The data strengthen the view that primary responses of Lyt-2+ cells do not require the presence of Ia+ cells.This publication has 6 references indexed in Scilit:
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