Trends in the treatment of patients with myocardial infarction and coronary revascularization procedures in Finland during 1986–92: the FINMONICA Myocardial Infarction Register Study
- 1 January 1999
- journal article
- research article
- Published by Wiley in Journal of Internal Medicine
- Vol. 245 (1), 107-108
- https://doi.org/10.1046/j.1365-2796.1999.00428.x
Abstract
Miettinen H, Salomaa V, Ketonen M, Niemelä M, Immonen‐Räihä P, Mähönen M, of the FINMONICA Myocardial Infarction Register Group (Kuopio University Hospital, Kuopio; National Public Health Institute, Helsinki; North Karelia Central Hospital, Joensuu; Loimaa District Hospital, Loimaa; and Turku University Hospital, Turku, Finland). Trends in the treatment of patients with myocardial infarction and coronary revascularization procedures in Finland during 1986–92: the FINMONICA Myocardial Infarction Register Study. J Intern Med 1999; 245: 11–20. Objectives. To investigate changes in the medical treatment of patients with myocardial infarction and the trends in revascularization procedures in Finland. Design. A population‐based myocardial infarction (MI) register study. Setting. Populations, aged 25–64 years, of the three geographical areas of Finland, provinces of North Karelia and Kuopio in eastern Finland and the Turku‐Loimaa area in south‐western Finland. Main outcome measures. Medical treatment administered prior to the coronary event, during the hospitalization and at discharge from hospital to all patients hospitalized due to suspected myocardial infarction and all CAD deaths occurring during three separate 4‐month periods in 1986, 1989 and 1992. Data on coronary bypass surgery and percutaneous coronary angioplasty in the study areas for 1986–92. Results. The most marked change in the medical treatment of hospitalized myocardial infarction patients was the significant increase in the use of thrombolytic treatment (5% of patients in 1986 and 24% in 1992, P < 0.001 for trend). The use of antiplatelet agents increased from 1986 to 1992 prior to the coronary event, during the hospitalization and at discharge. The use of beta‐blockers and intravenous nitrates increased and the use of calcium‐channel blockers declined significantly in hospitalized patients during the study period. Hospitalized male myocardial infarction patients were treated more often with beta‐blockers, nitrates, antiplatelet agents and thrombolytic agents than female patients, suggesting less intensive medical treatment in women. Conclusion. The results of the large clinical trials regarding the medical treatment of myocardial infarction patients were adopted in the clinical practice rapidly and the treatment of myocardial infarction patients and the number of revascularization procedures changed markedly from 1986 to 1992 in Finland. These changes may in part explain the favourable changes in mortality from CAD in Finland.Keywords
This publication has 30 references indexed in Scilit:
- Hospital care and survival of acute myocardial infarction patients in Minnesota and southern GermanyCoronary Artery Disease, 1996
- Selection factors for the use of thrombolytic treatment in acute myocardial infarction: a population based study of current practice in the United Kingdom. The European Secondary Prevention Study Group.Heart, 1995
- Myocardial Infarction Case-Fatality Gradient in Three French Regions: The Influence of Acute Coronary CareInternational Journal of Epidemiology, 1994
- Diagnosis of acute myocardial infarction by Monica and Finmonica diagnostic criteria in comparison with hospital discharge diagnosisJournal of Clinical Epidemiology, 1994
- Indications for fibrinolytic therapy in suspected acute myocardial infarction: collaborative overview of early mortality and major morbidity results from all randomised trials of more than 1000 patientsThe Lancet, 1994
- Impact of clinical trials on clinical practice: example of thrombolysis for acute myocardial infarctionThe Lancet, 1993
- Effect of verapamil on mortality and major events after acute myocardial infarction (The Danish Verapamil Infarction Trial II — DAVIT II)The American Journal of Cardiology, 1990
- Calcium channel blockers in acute myocardial infarction and unstable angina: an overview.BMJ, 1989
- The world health organization monica project (monitoring trends and determinants in cardiovascular disease): A major international collaborationJournal of Clinical Epidemiology, 1988
- Diltiazem and Reinfarction in Patients with Non-Q-Wave Myocardial InfarctionNew England Journal of Medicine, 1986