Red blood cell ATP/ADP & nitric oxide: The best vasodilators in diabetic patients
Open Access
- 24 August 2012
- journal article
- Published by Springer Science and Business Media LLC in Journal of Diabetes & Metabolic Disorders
- Vol. 11 (1), 9
- https://doi.org/10.1186/2251-6581-11-9
Abstract
Diabetes mellitus is a group of metabolic diseases characterized by high blood sugar (glucose) levels that result from defects in insulin secretion, or action, or both. Inspired by previous report the release of ATP from RBCs, which may participate in vessel dilation by stimulating NO production in the endothelium through purinergic receptor signaling and so, the aim of this study is to clearly determined relationship between RBC ATP/ADP ratio with nitric oxide.Keywords
This publication has 45 references indexed in Scilit:
- Exercise training enhanced myocardial endothelial nitric oxide synthase (eNOS) function in diabetic Goto-Kakizaki (GK) ratsCardiovascular Diabetology, 2008
- PGC-1α: a key regulator of energy metabolismAdvances in Physiology Education, 2006
- Red blood cell dysfunction in septic glucose-6-phosphate dehydrogenase-deficient miceAmerican Journal of Physiology-Heart and Circulatory Physiology, 2004
- Measurement of Nitric Oxide Production in Biological Systems by Using Griess Reaction AssaySensors, 2003
- Endothelial dysfunction in diabetesBritish Journal of Pharmacology, 2000
- Mechanisms Controlling Mitochondrial Biogenesis and Respiration through the Thermogenic Coactivator PGC-1Cell, 1999
- Evaluation of the mechanism of endothelial dysfunction in the genetically-diabetic BB ratLife Sciences, 1996
- Mechanisms of Flow-Mediated Signal Transduction in Endothelial Cells: Kinetics of ATP Surface ConcentrationsJournal of Vascular Research, 1992
- Bradykinin and ATP stimulate L-arginine uptake and nitric oxide release in vascular endothelial cellsBiochemical and Biophysical Research Communications, 1991
- Muscle metabolism and red cell ATP/ADP concentration during bicycle ergometer in patients with AMPD-deficiencyKlinische Wochenschrift, 1991