Oncogene expression in human tumors
- 15 June 1985
- journal article
- research article
- Published by Wiley in International Journal of Cancer
- Vol. 35 (6), 731-736
- https://doi.org/10.1002/ijc.2910350606
Abstract
The expression of 9 oncogenes in primary tumors and in human tumors passaged in nude mice was tested: a total of 28 tumor types was analyzed. Oncogenes src, fps, and mos were not expressed in any of the tumors tested but oncogene myc was transcribed in most of the tumors and myc was overexpressed in 3 tumors passaged in nude mice (Ewing sarcoma, large intestine carcinoma and kidney carcinoma) and in primary fibrous histiocytoma. Enhanced transcription of ras and fos genes was observed nonspecifically in different tumors. Oncogene sis was activated specifically in metastases of different tumors in lymph nodes.This publication has 25 references indexed in Scilit:
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