COMPARISON OF REACTIONS OF ANTIBODIES TO RAT COLLAGEN AND TO RAT KIDNEY IN THE BASEMENT MEMBRANES OF RAT RENAL GLOMERULI
Open Access
- 1 June 1969
- journal article
- Published by Rockefeller University Press in The Journal of Experimental Medicine
- Vol. 129 (6), 1145-1161
- https://doi.org/10.1084/jem.129.6.1145
Abstract
By in vivo and in vitro methods of immunofluorescence, antibody to rat collagen and to rat kidney show the same regular, linear fluorescence following the outlines of the renal glomerular capillaries. Absorption of each antiserum with its homologous antigen completely removed the antibody for immunofluorescence, while absorption with the heterologous antigen had no effect. The nephrotoxicity persisted in the anti-kidney serum absorbed with collagen.Keywords
This publication has 19 references indexed in Scilit:
- Isolation and characterization of the collagen from glomerular basement membraneBiochemistry, 1968
- STUDIES ON RENAL GLOMERULAR BASEMENT MEMBRANE - PREPARATION AND CHEMICAL COMPOSITION1967
- Studies on Glomerular Basement Membrane. 1. Isolation and Chemical Analysis of Normal Glomerular Basement Membrane.Experimental Biology and Medicine, 1966
- Collagen in normal rat glomeruliJournal of Ultrastructure Research, 1961
- Collagen Fibrils within the Renal GlomerulusThe Journal of cell biology, 1960
- RENAL GLOMERULAR LESIONS INDUCED BY RABBIT ANTI-RAT COLLAGEN SERUM IN RATS PREPARED WITH ADJUVANTThe Journal of Experimental Medicine, 1959
- THE ANTIGENICITY OF RAT COLLAGENThe Journal of Experimental Medicine, 1954
- LOCALIZATION OF ANTIGEN IN TISSUE CELLSThe Journal of Experimental Medicine, 1950
- THE PRODUCTION OF CHRONIC GLOMERULONEPHRITIS IN RATS BY THE INJECTION OF RABBIT ANTI-RAT-PLACENTA SERUM.1946