Induction in Primary Culture of ‘Gluconeogenic’ and ‘Glycolytic’ Hepatocytes Resembling Periportal and Perivenous Cells
- 1 August 1982
- journal article
- research article
- Published by Wiley in European Journal of Biochemistry
- Vol. 126 (2), 271-278
- https://doi.org/10.1111/j.1432-1033.1982.tb06775.x
Abstract
Adult rat hepatocytes were kept in primary culture for 48 h under different hormonal conditions to induce an enzyme pattern which with respect to carbohydrate metabolism approximated that of periportal and perivenous hepatocytes in vivo. The results support the view that periportal and perivenous hepatocytes in vivo catalyse gluconeogenesis and glycolysis at inverse rates.This publication has 64 references indexed in Scilit:
- Inactivation of liver phosphofructokinase by phosphofructokinase phosphatase or by low pH is inhibited by fructose 2,6‐bisphosphateFEBS Letters, 1981
- Control of Glycogen Metabolism by Insulin in Isolated HepatocytesHormone and Metabolic Research, 1981
- Induction of phosphoenolpyruvate carboxykinase by sympathetic agents in primary cultures of adult rat hepatocytesBiochemical and Biophysical Research Communications, 1981
- What is the molecular basis for the action of insulin?Trends in Biochemical Sciences, 1979
- Induction of glucokinase by insulin under the permissive action of dexamethasone in primary rat hepatocyte culturesBiochemical and Biophysical Research Communications, 1979
- Heterogeneous reciprocal localization of fructose‐1,6‐bis‐phosphatase and of glucokinase in microdissected periportal and perivenous rat liver tissueFEBS Letters, 1977
- Blood glucose levels in portal and peripheral circulation and their relation to food intake in the ratPhysiology & Behavior, 1977
- Heterogeneous distribution of glucose‐6‐phosphatase in microdissected periportal and perivenous rat liver tissueFEBS Letters, 1977
- Functional heterogeneity of rat liver parenchyma and of isolated hepatocytesFEBS Letters, 1975
- Isolation of rat liver cells containing Concanavalin‐A receptor sitesFEBS Letters, 1974