Is the observed association between periodontitis and atherosclerosis causal?
- 1 February 2001
- journal article
- review article
- Published by Wiley in European Journal of Oral Sciences
- Vol. 109 (1), 2-7
- https://doi.org/10.1034/j.1600-0722.2001.109001002.x
Abstract
Most of the documentation of possible causal links between periodontitis and atherosclerosis-related diseases appears indirect or circumstantial. There is, however, an increasing number of both experimental and longitudinal epidemiological studies which seem to support a causal relationship. A critical evaluation of the epidemiological data available might therefore be appropriate. The present study is based on a literature search using Ovid medical data base covering the period from 1989 to October 2000 and applying specific inclusion criteria. Based on a critical evaluation of the 14 investigations selected from a total of 21 retrieved from the search, a causal relationship between periodontitis and atherosclerosis-related diseases appeared possible. However, the nature both of periodontitis and atherosclerosis is multifactorial, and caution should be exercised when implicating periodontal disease in the causation of atherosclerotic disorders.Keywords
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