In vivo nuclear magnetic resonance chemical shift imaging by selective irradiation.
- 1 November 1984
- journal article
- research article
- Published by Proceedings of the National Academy of Sciences in Proceedings of the National Academy of Sciences of the United States of America
- Vol. 81 (21), 6856-6860
- https://doi.org/10.1073/pnas.81.21.6856
Abstract
NMR images of preselected chemically shifted species can be obtained by selective irradiation of the remainder of the NMR chemical shift spectrum prior to applicatoin of a conventional NMR imaging sequence. The chemical-selective irradiation consists of narrow-bandwidth .pi./2 or saturation radio-frequency pulses applied in the absence of imaging gradients. The technique permits substantial reductions in scan and reconstruction times over standard 3- and 4-dimensional Fourier transform chemical-shift-imaging methods, when images of few spectral peaks are desired. It is also suitable for the elimination of chemical shift artifacts in conventional high-field NMR imaging. In vivo applications of the technique to the head and limbs in a 1.5-T magnetic field yield 1H H2O and -CH2-images, with little detectable -CH2- in muscle and brain.This publication has 18 references indexed in Scilit:
- Spatial localization in 31P and 13C NMR spectroscopy in Vivo using surface coilsMagnetic Resonance in Medicine, 1984
- High-resolution 1H nuclear magnetic resonance study of cerebral hypoxia in vivo.Proceedings of the National Academy of Sciences, 1983
- NMR IMAGING/SPECTROSCOPY SYSTEM TO STUDY BOTH ANATOMY AND METABOLISMThe Lancet, 1983
- Signal, Noise, and Contrast in Nuclear Magnetic Resonance (NMR) ImagingJournal of Computer Assisted Tomography, 1983
- NON-INVASIVE INVESTIGATION OF CEREBRAL METABOLISM IN NEWBORN INFANTS BY PHOSPHORUS NUCLEAR MAGNETIC RESONANCE SPECTROSCOPYThe Lancet, 1983
- CLINICAL USE OF NUCLEAR MAGNETIC RESONANCE IN THE INVESTIGATION OF MYOPATHYThe Lancet, 1982
- 31P NMR examination of two patients with NADH-CoQ reductase deficiencyNature, 1982
- In-vivo soft tissue NMR imaging of the rat thorax and abdomenCellular and Molecular Life Sciences, 1981
- Examination of a Case of Suspected McArdle's Syndrome by31P Nuclear Magnetic ResonanceNew England Journal of Medicine, 1981
- Adenosine triphosphate compartmentation in living hearts: a phosphorus nuclear magnetic resonance saturation transfer studyBiochemistry, 1979