Radiation Recall Dermatitis After Pre-Sensitization With Pegylated Liposomal Doxorubicin
- 1 January 2009
- journal article
- case report
- Published by Informa UK Limited in Cancer Investigation
- Vol. 27 (4), 397-401
- https://doi.org/10.1080/07357900802392667
Abstract
Radiation recall dermatitis (RRD) is a rare cutaneous reaction occurring within a previously irradiated field, precipitated by certain drugs. We report a case of RRD occurring after pre-sensitization with pegylated liposomal doxorubicin (PLD) in a woman with Stage IV breast cancer. The RRD occurred in one of the patient's four previous radiotherapy fields. We discuss the time/dose factors of radiation exposure and measure the corresponding skin dose. In our case the radiation dose was low and below previously reported thresholds, and illustrates that there is a more complex interaction between the radiotherapy and the trigger agent than has previously been considered.Keywords
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