Morphologic Criteria for the Prognosis of Serous Cystadenocarcinoma of the Ovary

Abstract

143 cases of serous ovarian cystadenocarcinoma were studied to establish the prognostic relevance of specific macroscopic and microscopic criteria. Significant differences in the survival rate were found depening on TNM classification, age, residual tumor mass, ascites, and degree of invasion. The prognosis was significantly better for normotypical or predominantly cystic tumors as well as for those with mononuclear infiltration, little histological atypia, or limited invasion. No prognostic relevance was found, however, for cytologic criteria such as Broder’s grading and rate of mitosis.