Epstein-Barr Virus: Detection of Genome in Somatic Cell Hybrids of Burkitt Lymphoblastoid Cells
- 2 February 1973
- journal article
- other
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 179 (4072), 492-493
- https://doi.org/10.1126/science.179.4072.492
Abstract
Somatic cell hybrids of Burkitt lymphoblastoid cells, from which Epstein-Barr virus can be recovered, were examined for the presence of virus DNA by DNA-RNA hybridization. Four clones of hybrid cells, each negative for virus antigens by immunofluorescence, contained virus DNA in varying genomic equivalents. The number of virus genome equivalents increased in the hybrid cells after induction of virus with iododeoxyuridine.Keywords
This publication has 6 references indexed in Scilit:
- Rescue of Epstein-Barr Virus from Somatic Cell Hybrids of Burkitt Lymphoblastoid CellsJournal of Virology, 1972
- Hybridization of Burkitt Lymphoblastoid CellsScience, 1972
- Detection of Epstein-Barr Viral Genome in Nonproductive CellsNature New Biology, 1971
- Presence of EB Virus Nucleic Acid Homology in a “Virus-free” Line of Burkitt Tumour CellsNature, 1970
- MORPHOLOGICAL AND BIOLOGICAL STUDIES ON A VIRUS IN CULTURED LYMPHOBLASTS FROM BURKITT'S LYMPHOMAThe Journal of Experimental Medicine, 1965
- Selection of Hybrids from Matings of Fibroblasts in vitro and Their Presumed RecombinantsScience, 1964