In Vitro Activities of Isepamicin, Other Aminoglycosides, and Capreomycin against Clinical Isolates of Rapidly Growing Mycobacteria in Taiwan

Abstract

The in vitro activities of isepamicin against 117 Mycobacteria abscessus , 48 Mycobacterium fortuitum , and 20 Mycobacterium chelonae isolates were evaluated by a microdilution test. Isepamicin MIC ₉₀ s were ≤16 μg/ml for the three species. Isepamicin was as active as amikacin and kanamycin and more active than tobramycin, capreomycin, gentamicin, and streptomycin.