Two-tiered regulation of spatially patterned engrailed gene expression during Drosophila embryogenesis
- 1 April 1988
- journal article
- review article
- Published by Springer Science and Business Media LLC in Nature
- Vol. 332 (6165), 604-609
- https://doi.org/10.1038/332604a0
Abstract
A regulatory cascade, initiated during the syncytial stage of embryogenesis, culminates in the striped pattern of engrailed gene expression at the cellular blastoderm stage. The early regulatory genes, for example the pair-rule genes, are expressed transiently and as their products decay a distinct regulatory programme involving segment polarity genes takes over. This late programme maintains and perhaps modifies the striped pattern of engrailed expression through interactions that may involve cell communication.Keywords
This publication has 36 references indexed in Scilit:
- Complementary patterns of even-skipped and fushi tarazu expression involve their differential regulation by a common set of segmentation genes in Drosophila.Genes & Development, 1987
- Autonomous requirements for the segment polarity gene armadillo during Drosophila embryogenesisCell, 1987
- Multiple functions of segment polarity genes in DrosophilaDevelopmental Biology, 1987
- Isolation, structure, and expression of even-skipped: A second pair-rule gene of Drosophila containing a homeo boxCell, 1986
- Isolation of a homoeo box-containing gene from the engrailed region of Drosophila and the spatial distribution of its transcriptsNature, 1985
- The engrailed locus of drosophila: Structural analysis of an embryonic transcriptCell, 1985
- Transposition of Cloned P Elements into Drosophila Germ Line ChromosomesScience, 1982
- Regeneration of the segment boundary in OncopeltusDevelopmental Biology, 1981
- Mutations affecting segment number and polarity in DrosophilaNature, 1980
- The development of wingless, a homeotic mutation of DrosophilaDevelopmental Biology, 1977