Cytomegalovirus infection in transplant recipients
Top Cited Papers
Open Access
- 1 July 2015
- journal article
- review article
- Published by Elsevier BV in Clinics
- Vol. 70 (7), 515-523
- https://doi.org/10.6061/clinics/2015(07)09
Abstract
Cytomegalovirus infection is a frequent complication after transplantation. This infection occurs due to transmission from the transplanted organ, due to reactivation of latent infection, or after a primary infection in seronegative patients and can be defined as follows: latent infection, active infection, viral syndrome or invasive disease. This condition occurs mainly between 30 and 90 days after transplantation. In hematopoietic stem cell transplantation in particular, infection usually occurs within the first 30 days after transplantation and in the presence of graft-versus-host disease. The major risk factors are when the recipient is cytomegalovirus seronegative and the donor is seropositive as well as when lymphocyte-depleting antibodies are used.Keywords
This publication has 81 references indexed in Scilit:
- Clinical Assessment of Anti-Viral CD8+ T Cell Immune Monitoring Using QuantiFERON-CMV® Assay to Identify High Risk Allogeneic Hematopoietic Stem Cell Transplant Patients with CMV Infection ComplicationsPLOS ONE, 2013
- Updated International Consensus Guidelines on the Management of Cytomegalovirus in Solid-Organ TransplantationTransplantation, 2013
- Cytomegalovirus in Solid Organ TransplantationAmerican Journal of Transplantation, 2013
- Clinical significance of quantitative cytomegalovirus detection in bronchoalveolar lavage fluid in lung transplant recipientsTransplant Infectious Disease, 2012
- Risk factors and clinical outcomes of cytomegalovirus disease occurring more than one year post solid organ transplantationTransplant Infectious Disease, 2012
- GESITRA-SEIMC/REIPI recommendations for the management of cytomegalovirus infection in solid-organ transplant patientsEnfermedades Infecciosas y Microbiología Clínica, 2011
- Cytomegalovirus: pathogen, paradigm, and puzzleJCI Insight, 2011
- Impact of Prophylactic Versus Preemptive Valganciclovir on Long-Term Renal Allograft OutcomesTransplantation, 2010
- Quantification of DNA in Plasma by an Automated Real-Time PCR Assay (Cytomegalovirus PCR Kit) for Surveillance of Active Cytomegalovirus Infection and Guidance of Preemptive Therapy for Allogeneic Hematopoietic Stem Cell Transplant RecipientsJournal of Clinical Microbiology, 2008
- Improving Outcomes for Solid-Organ Transplant Recipients At Risk from Cytomegalovirus Infection: Late-Onset Disease and Indirect ConsequencesClinical Infectious Diseases, 2008