Otitis Media Secondary to Ampicillin-Resistant Hemophilus Influenzae

Abstract
During a 2-year period ending December 1978, we encountered 27 cases of otitis media secondary to ampicillin-resistant Hemophilus influenzae. This represents 19% of the 139 Hemophilus isolates obtained by tympanocentesis. In agreement with data from Huntsville, Alabama, Boston, and Pittsburgh, we estimate that as of 1978, approximately 4% of all cases of acute otitis media are caused by this pathogen.